Bruno Stroszek is released from prison and warned to stop drinking. He has few skills and fewer expectations: with a glockenspiel and an accordion, he ekes out a living as a street musician. He befriends Eva, a prostitute down on her luck. After they are harried and beaten by the thugs who have been Eva's pimps, they join Bruno's neighbor, Scheitz, an elderly eccentric, when he leaves Germany to live in Wisconsin. In that winter bound, barren prairie, Bruno works as a mechanic, Eva as a waitress. They buy a trailer. Then, bills mount, the bank threatens to repossess the trailer, Eva wants privacy, and inexorably, the promise of a new life deserts Bruno.

Husband, wife, and daughter have moved from Boston to Williamstown. At 16, Samantha treats her mother shabbily, but when the two of them are in a horrific car crash, the mother wills Sam to live, somehow losing her own life while her spirit enters Sam. Can she convince husband Ben that she's his wife inside his daughter's body, what if he believes her, and can she live Samantha's life (discovering all her daughter's secrets) while she figures out what to do? What's Ben's part in this secret life?